Description

4-Fluoro-D-Mandelic Acid is a high-purity chiral building block and key intermediate in advanced organic synthesis. This compound is valued for its role in the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector requiring enantiomerically pure intermediates for APIs, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced, optically active herbicides, fungicides, and pesticides.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Utilized as a standard or reagent in enzymatic studies and metabolic pathway investigations.
• Material Science: A potential monomer or modifier for creating polymers with specific optical or physical properties.

Basic Information

Product Name	4-Fluoro-D-Mandelic Acid
CAS No.	32222-45-0
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	(R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid; D-4-Fluoromandelic Acid; (R)-4-Fluoromandelic Acid; (R)-(-)-4-Fluoromandelic Acid; (2R)-2-Hydroxy-2-(4-fluorophenyl)acetic Acid; 4-Fluoro-D-α-Hydroxyphenylacetic Acid; p-Fluoro-D-mandelic Acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-D-Mandelic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.