Description

Methyl o-Methyl-D-(-)-Mandelate is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiopure active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Serves as a starting material or resolving agent in stereoselective reactions to construct complex molecular architectures.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & R&D: A standard reagent in university and industrial research laboratories for methodological studies in organic and medicinal chemistry.
• Catalyst Ligand Preparation: Potential precursor for synthesizing chiral ligands used in homogeneous catalysis.

Basic Information

Product Name	Methyl o-Methyl-D-(-)-Mandelate
CAS No.	32174-46-2
Molecular Formula	C11H14O4
Molecular Weight	210.23 g/mol
Synonyms	D-(-)-Methyl 2-Methoxymandelate; (R)-(-)-Methyl 2-Methoxymandelate; Methyl (R)-2-Methoxymandelate; (R)-Methyl 2-Methoxymandelate; Methyl (R)-(-)-2-Methoxymandelate; 2-Methoxy-α-hydroxybenzeneacetic acid methyl ester, (R)-; Mandelic acid, 2-methoxy-, methyl ester, (R)-
EINECS	Contact for details

Quality Control

Our Methyl o-Methyl-D-(-)-Mandelate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.