Description

R-Butyrolactone is a versatile chiral lactone and a key intermediate in organic synthesis. Its defined stereochemistry makes it a critical building block for producing high-value, optically active pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereocenters into complex molecules. The product is supplied as R-Butyrolactone CAS NO 32082-74-9.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for synthesizing active pharmaceutical ingredients (APIs), particularly in the production of statins, antivirals, and other stereospecific drugs.
• Agrochemical Synthesis: Used in the manufacture of chiral pesticides and herbicides where specific enantiomeric activity is required for efficacy and environmental safety.
• Fine Chemical Production: Serves as a starting material for flavors, fragrances, and advanced materials that require the (R)-enantiomer configuration.
• Polymer Modification: Employed in the synthesis of specialized polymers and resins, imparting specific properties through its lactone functionality.
• Asymmetric Synthesis: A valuable reagent in academic and industrial research for developing new catalytic asymmetric reactions and methodologies.

Basic Information

Product Name	R-Butyrolactone
CAS No.	32082-74-9
Molecular Formula	C4H6O2
Molecular Weight	86.09 g/mol
Synonyms	(R)-γ-Butyrolactone; (R)-Dihydro-2(3H)-furanone; (R)-GBL; (R)-4-Butanolide; (R)-Tetrahydro-2-furanone; (3R)-Dihydrofuran-2(3H)-one; (R)-1,4-Butanolide; (R)-Butan-4-olide
EINECS	Contact for details

Quality Control

Our R-Butyrolactone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for identity, assay, and enantiomeric excess are provided to guarantee reliable performance and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (R)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.