Description

Salazopyrine is a sulfonamide-based pharmaceutical compound, primarily recognized for its anti-inflammatory and immunomodulatory properties. Its core value lies in its established efficacy for managing chronic inflammatory conditions, offering a critical therapeutic option. This product is essential for pharmaceutical manufacturers, research institutions, and compounding facilities developing treatments for autoimmune and gastrointestinal disorders. Salazopyrine CAS NO 31363-03-8 represents a key active pharmaceutical ingredient (API) with a well-documented clinical profile.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of oral tablets and enteric-coated tablets for the treatment of ulcerative colitis and rheumatoid arthritis.
• Autoimmune Disease Management: Used in the development of medications for Crohn's disease and ankylosing spondylitis.
• Research & Development: Serves as a critical reference standard and building block in medicinal chemistry research for novel anti-inflammatory agents.
• Veterinary Pharmaceuticals: Applied in certain veterinary formulations for inflammatory conditions in animals.
• Compounding Pharmacy: Utilized by specialized pharmacies to prepare customized dosage forms for patients with specific needs.

Basic Information

Product Name	Salazopyrine
CAS No.	31363-03-8
Molecular Formula	C18H14N4O5S
Molecular Weight	398.39 g/mol
Synonyms	Salazosulfapyridine; Sulfasalazine; 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic acid; Azulfidine® (brand name); Salicylazosulfapyridine; SASP; Azopyrine; Salazopyrin
EINECS	250-563-1

Quality Control

Our Salazopyrine is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, purity, and impurity profiles using validated methods such as HPLC and titration. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with cGMP guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	NMT 1.0%
Residue on Ignition	NMT 0.1%
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.