Description

Pyrazofurin is a synthetic nucleoside analog with significant antiviral and antineoplastic research applications. Its primary value lies in its potent inhibition of inosine monophosphate dehydrogenase (IMPDH), a key enzyme in the *de novo* biosynthesis of guanine nucleotides. This mechanism makes it a critical compound for researchers in pharmaceutical development and life sciences, particularly for studying antiviral therapies and cancer cell metabolism. Global B2B clients in advanced intermediates, contract research organizations (CROs), and academic institutions rely on high-purity Pyrazofurin for their investigative and development programs.

Application

• Antiviral Research: Investigated for its activity against a range of DNA and RNA viruses in preclinical studies.
• Oncology Research: Used as a tool compound to study cell proliferation, apoptosis, and nucleotide metabolism in various cancer cell lines.
• Biochemical Assay Development: Serves as a standard or inhibitor in enzymatic assays targeting IMP dehydrogenase.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex nucleoside-based drug candidates.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in virology and biochemistry.
• Reference Standard: Used in analytical laboratories for method development and quality control of related substances.

Basic Information

Product Name	Pyrazofurin
CAS No.	30868-30-5
Molecular Formula	C9H11N3O5
Molecular Weight	241.20 g/mol
Synonyms	Pyrazofurin; Pyrazomycin; 4-Hydroxy-3-β-D-ribofuranosyl-1H-pyrazole-5-carboxamide; 3-β-D-Ribofuranosyl-4-hydroxy-1H-pyrazole-5-carboxamide; NSC 143095; U-42126; Antibiotic U 42126; Pyrazofurine
EINECS	Contact for details

Quality Control

Our Pyrazofurin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing including identification, assay, and impurity profiling. A detailed Certificate of Analysis (COA) documenting purity (typically ≥95% to ≥98% by HPLC), residual solvents, and other critical parameters is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.