Description

3-Dansylestrone is a dansyl-labeled derivative of the natural estrogen, estrone, designed for high-sensitivity detection and analysis. This compound is valued for its strong fluorescence properties, making it an essential tool for advanced biochemical research and analytical method development. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors for applications requiring precise estrogen detection and quantification.

Application

• Fluorescent Labeling Agent: Used as a derivatization reagent for the sensitive HPLC or LC-MS analysis of estrogens and related steroids.
• Biochemical Research: Serves as a fluorescent probe in receptor binding studies, enzyme assays, and metabolic pathway investigations involving estrogenic compounds.
• Analytical Standard: Employed as a certified reference material (CRM) for calibrating instruments and validating analytical methods in regulatory and quality control environments.
• Pharmaceutical Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for estrogen-based therapeutics through its traceable fluorescent tag.
• Diagnostic Assay Development: Acts as a key component in developing fluorescence-based immunoassays or biosensors for clinical and environmental hormone monitoring.

Basic Information

Product Name	3-Dansylestrone
CAS No.	30804-69-4
Molecular Formula	C28H31NO3S
Molecular Weight	461.62 g/mol
Synonyms	Dansyl Estrone; Estrone 3-dansylate; 3-(5-Dimethylaminonaphthalene-1-sulfonamido)estra-1,3,5(10)-trien-17-one; 17-Oxo-3-[(5-dimethylaminonaphthalene-1-sulfonyl)amino]estra-1,3,5(10)-triene; Estrone Dansyl Derivative; DNS-Estrone
EINECS	Contact for details

Quality Control

Every batch of 3-Dansylestrone is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for high-purity biochemicals. Comprehensive testing includes identity confirmation, purity assay, and impurity profiling. A detailed Certificate of Analysis (COA) providing batch-specific results is available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, acetonitrile; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.