Description

Potassium 2-(Trifluoromethyl)Phenyltrifluoroborate is a high-value organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, widely used in synthesizing complex organic molecules, including drug candidates and agrochemical intermediates.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block for introducing the 2-(trifluoromethyl)phenyl moiety, a common pharmacophore in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require precise aromatic fluorinated components.
• Catalyst and Ligand Preparation: Acts as a precursor for creating specialized catalysts and ligands used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Medicinal Chemistry: Utilized in the discovery and optimization of new chemical entities through parallel synthesis and library development.

Basic Information

Item	Details
Product Name	Potassium 2-(Trifluoromethyl)Phenyltrifluoroborate
CAS No.	30678-36-5
Molecular Formula	C7H4BF6K
Molecular Weight	252.01 g/mol
Synonyms	Potassium (2-(Trifluoromethyl)phenyl)trifluoroborate; Potassium 2-(Trifluoromethyl)benzenetrifluoroborate; 2-(Trifluoromethyl)phenyltrifluoroborate Potassium Salt; (2-Trifluoromethylphenyl)trifluoroboronic Acid Potassium Salt; Potassium Trifluoro(2-(trifluoromethyl)phenyl)borate; 2-CF3C6H4BF3K; Potassium α,α,α-Trifluoro-o-tolyltrifluoroborate
EINECS	Contact for details

Quality Control

Our production of Potassium 2-(Trifluoromethyl)Phenyltrifluoroborate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analysis, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and KF titration, to verify identity, purity, and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (¹H)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.