Description

Methyl (R)-(-)-3-Hydroxybutyrate is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This optically active ester is a key precursor for the production of pharmaceuticals, fine chemicals, and advanced materials where stereochemical control is paramount. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of β-blockers, antibiotics, and other active pharmaceutical ingredients (APIs) requiring the (R)-configuration.
• Fine Chemical Synthesis: Used in the preparation of flavors, fragrances, and other high-value specialty chemicals where optical purity defines product quality.
• Agrochemical Production: Serves as a building block for chiral pesticides and herbicides, where the specific enantiomer can dictate biological activity and environmental safety.
• Biochemical Research: Employed in metabolic studies and as a precursor for synthesizing analogs of biologically active molecules like (R)-3-hydroxybutyric acid.
• Polymer Science: Can be utilized as a monomer or co-monomer in the development of biodegradable or functional polymers with specific stereochemistry.
• Asymmetric Catalysis: Acts as a substrate or ligand precursor in catalytic reactions to induce chirality in target molecules.

Basic Information

Product Name	Methyl (R)-(-)-3-Hydroxybutyrate
CAS No.	3976-69-0
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(R)-(-)-3-Hydroxybutyric Acid Methyl Ester; Methyl (R)-3-Hydroxybutyrate; (R)-Methyl 3-Hydroxybutanoate; (R)-3-Hydroxybutanoic Acid Methyl Ester; (R)-MHB; (R)-(-)-β-Hydroxybutyric Acid Methyl Ester; (R)-Methyl β-Hydroxybutyrate
EINECS	223-607-7

Quality Control

Our Methyl (R)-(-)-3-Hydroxybutyrate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (R)
Specific Rotation [α]	-20° to -24° (c=1, CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.