Description

(S)-2-Benzylsuccinic Acid is a high-purity chiral organic acid of significant interest in advanced chemical synthesis. This compound serves as a crucial chiral building block and resolving agent for the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or resolving agent for the production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for asymmetric catalysis, enhancing stereoselectivity in chemical reactions.
• Fine Chemical and Agrochemical Building Block: Employed in the synthesis of complex, high-value specialty chemicals and chiral agrochemicals.
• Academic and Industrial Research: Serves as a standard or reagent in methodological development for stereoselective synthesis and chiral separation studies.
• Resolution of Racemic Mixtures: Acts as a classical resolving agent for the separation of racemic amines or other basic compounds due to its acidic functionality and chiral center.

Basic Information

Product Name	(S)-2-Benzylsuccinic Acid
CAS No.	3972-36-9
Molecular Formula	C11H12O4
Molecular Weight	208.21 g/mol
Synonyms	(S)-2-Benzylbutanedioic Acid; (S)-α-Benzylsuccinic Acid; (2S)-2-Benzylsuccinic Acid; (S)-(+)-2-Benzylsuccinic Acid; L-2-Benzylsuccinic Acid; (S)-2-(Phenylmethyl)butanedioic Acid; Benzylsuccinic Acid, (S)-; Butanedioic acid, 2-(phenylmethyl)-, (2S)-
EINECS	Contact for details

Quality Control

Our (S)-2-Benzylsuccinic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity (enantiomeric excess) verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.