Description

Inosine-8-14C is a carbon-14 labeled isotopologue of the nucleoside inosine, specifically radiolabeled at the 8-position of the purine base. This compound is a critical tool for conducting precise metabolic and pharmacokinetic studies, enabling researchers to trace biochemical pathways with high specificity. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for applications in drug development and biochemical research.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of novel pharmaceutical compounds.
• Nucleic Acid Metabolism Research: Employed as a radiolabeled precursor to study purine salvage pathways, nucleotide synthesis, and degradation.
• Biochemical Pathway Analysis: Facilitates the elucidation of enzymatic mechanisms and metabolic fluxes in cellular systems.
• Quality Control and Reference Standard: Serves as an authenticated reference material in analytical laboratories for method development and validation.
• Environmental Fate Studies: Applied in research to track the degradation and transformation of nucleoside-based compounds in environmental samples.

Basic Information

Product Name	Inosine-8-14C
CAS No.	3926-71-4
Molecular Formula	C10H1214CN4O5
Molecular Weight	Contact for details
Synonyms	8-14C-Inosine; Inosine (8-14C); 9-β-D-Ribofuranosylhypoxanthine-8-14C; 6-Hydroxy-9-β-D-ribofuranosyl-9H-purine-8-14C; Hypoxanthine riboside-8-14C; 9H-Purin-6-ol, 9-β-D-ribofuranosyl-, 8-14C; Inosine-8-Carbon-14
EINECS	Contact for details

Quality Control

Every batch of Inosine-8-14C is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on radiochemical purity, chemical purity, and specific activity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at the recommended temperature of 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for specific value)
Solvent (for solution forms)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.