Description

D-Glucose-6-14C is a carbon-14 labeled isotopologue of D-glucose, a fundamental monosaccharide and primary energy source in biological systems. This radiolabeled compound is essential for precise metabolic pathway tracing and quantitative analysis in biochemical research. It is a critical reagent for scientists in pharmaceutical development, metabolic disease research, and plant physiology who require accurate tracking of glucose utilization and carbon flux.

Application

• Metabolic Pathway Analysis: Tracing the specific fate of glucose carbons in glycolysis, the pentose phosphate pathway, and gluconeogenesis.
• Drug Metabolism & Pharmacokinetics (DMPK): Studying the absorption, distribution, metabolism, and excretion (ADME) of new therapeutic compounds that interact with glucose pathways.
• Biomedical Research: Investigating glucose metabolism in models of diabetes, cancer (Warburg effect), and other metabolic disorders.
• Enzymology Studies: Serving as a labeled substrate for kinetic assays of enzymes like glucose-6-phosphate dehydrogenase and hexokinase.
• Plant & Microbial Physiology: Researching carbon fixation, photosynthesis, and carbohydrate metabolism in plants and microorganisms.
• Radiochemical Synthesis: Acting as a labeled precursor for the synthesis of more complex 14C-labeled carbohydrates and biomolecules.

Basic Information

Product Name	D-Glucose-6-14C
CAS No.	3573-62-4
Molecular Formula	C6H12O6 (with 14C at position 6)
Molecular Weight	~180.16 g/mol (exact mass depends on specific activity)
Synonyms	D-[6-14C]Glucose; [6-14C]D-Glucose; Glucose-6-14C; 14C-Glucose; Dextrose-6-14C; (6-14C)Glucose; D-Glucose (6-14C); Radioactive D-Glucose
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-6-14C is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed data on radiochemical purity, chemical purity, specific activity, and analytical method validation.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Follow all applicable local and international regulations for the safe storage and handling of radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR / HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC / TLC)	≥ 97%
Specific Activity	50-62 mCi/mmol (typical, custom activities available)
Solvent (if supplied as solution)	Ethanol:Water (specified ratio) or custom

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.