Description

[[5-(2-Amino-6-Oxo-3H-Purin-9-Yl)-3-Hydroxy-Oxolan-2-Yl]Methoxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid is a high-purity, biologically relevant nucleotide analog crucial for advanced biochemical research and pharmaceutical development. Its primary value lies in its role as a key intermediate or reference standard in the synthesis of modified nucleosides and nucleotides, enabling studies in virology, enzymology, and targeted drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require precise, reliable building blocks for nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate polymerase and kinase activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Proteomics & Genomics: Acts as a modified building block for oligonucleotide synthesis in probe and primer development.
• Drug Discovery: Integral to medicinal chemistry programs focused on developing nucleotide-based therapeutics.
• Academic Research: Utilized in university and institutional labs for fundamental research into nucleic acid metabolism and function.

Basic Information

Product Name	[[5-(2-Amino-6-Oxo-3H-Purin-9-Yl)-3-Hydroxy-Oxolan-2-Yl]Methoxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid
CAS No.	3493-09-2
Molecular Formula	C10H15N5O12P2
Molecular Weight	459.20 g/mol
Synonyms	9-[(2R,3S,5R)-3-Hydroxy-5-[[hydroxy(phosphonooxy)phosphinyl]oxy]methyl]oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate); dGTP; 2'-Deoxyguanosine-5'-triphosphate; Deoxyguanosine triphosphate; dGTP, trisodium salt (common salt form); 2'-Deoxy-GTP; Deoxyguanosine 5'-triphosphoric acid
EINECS	Contact for details

Quality Control

Every batch of our [[5-(2-Amino-6-Oxo-3H-Purin-9-Yl)-3-Hydroxy-Oxolan-2-Yl]Methoxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay by HPLC, identification by IR and NMR, and limits for related substances and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, keep containers sealed under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Individual impurity ≤1.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.