Description

3-(4-Fluorophenyl)Glutaric Acid is a high-purity fluorinated dicarboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the glutaric acid backbone combined with the electronic influence of the para-fluorophenyl substituent, enabling precise molecular construction. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors who require reliable, high-quality intermediates for complex syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where fluorinated compounds are advantageous.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, stability, and metabolic profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic molecules used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, modifying properties like thermal stability, chemical resistance, and surface characteristics.
• Organic Synthesis Reagent: Utilized in various name reactions and coupling chemistries as a dicarboxylic acid component or to introduce the 4-fluorophenyl moiety into more complex molecular architectures.
• Bioconjugation & Linker Chemistry: The carboxylic acid groups provide handles for conjugation, making it useful in creating chemical linkers for bioconjugation and prodrug development.

Basic Information

Product Name	3-(4-Fluorophenyl)Glutaric Acid
CAS No.	3449-63-6
Molecular Formula	C11H11FO4
Molecular Weight	226.20 g/mol
Synonyms	3-(4-Fluorophenyl)pentanedioic acid; 4-Fluorophenylglutaric acid; Glutaric acid, 3-(4-fluorophenyl)-; 3-(p-Fluorophenyl)glutaric acid; NSC 403714; 1,5-Pentanedioic acid, 3-(4-fluorophenyl)-; 3-(4-Fluorophenyl)-1,5-pentanedioic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Glutaric Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.