Description

Noxiptiline CAS NO 3362-45-6 is a tricyclic antidepressant (TCA) compound belonging to the dibenzoxepin class. It matters as a key pharmaceutical intermediate and reference standard for research into central nervous system (CNS) agents and neuropharmacology. This product is essential for pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in the synthesis, development, and quality control of psychotropic medications.

Application

• Pharmaceutical intermediate for the synthesis of antidepressant active pharmaceutical ingredients (APIs).
• Chemical reference standard for analytical method development and validation in quality control (QC) laboratories.
• Research and development of novel CNS-targeting therapeutic agents.
• Metabolite and impurity profiling studies for related pharmaceutical compounds.
• Preclinical pharmacological research to study the mechanism of action of tricyclic antidepressants.
• Building block in medicinal chemistry for creating new chemical entities with potential neuroactive properties.

Basic Information

Product Name	Noxiptiline
CAS No.	3362-45-6
Molecular Formula	C19H21NO
Molecular Weight	279.38 g/mol
Synonyms	Noxiptiline; Nogedon; Agedal; Bay 1521; 10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo[a,d]cycloheptene; 5-[(3-Methylaminopropylidene)]-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
EINECS	222-135-6

Quality Control

Our Noxiptiline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and mass spectrometry. The product is suitable for use as a pharmaceutical reference standard and intermediate, with purity levels tailored to meet specific R&D and QC requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound should be kept under inert conditions if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.