Description

L-Phenylglycinol is a versatile chiral amino alcohol and a key building block in organic synthesis. Its primary value lies in its utility as a chiral auxiliary and resolving agent for the asymmetric synthesis of pharmaceuticals and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where high enantiomeric purity is critical.

Application

• Pharmaceutical Intermediates: A crucial chiral building block for synthesizing active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce high enantioselectivity.
• Resolution of Racemates: Employed as a resolving agent for the separation of enantiomers from racemic mixtures.
• Agrochemical Synthesis: Serves as a precursor in the production of chiral pesticides and herbicides.
• Fine Chemical Production: Integral to the manufacture of complex molecules for flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A standard reagent in method development and process chemistry research within R&D laboratories.

Basic Information

Product Name	L-Phenylglycinol
CAS No.	3182-95-4
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(S)-2-Amino-2-phenylethanol; (S)-(-)-2-Phenylglycinol; L-2-Phenyl-2-hydroxyethylamine; (S)-2-Phenyl-2-aminoethanol; (1S)-2-Amino-1-phenylethanol; (S)-β-Amino-β-phenylethanol; (S)-2-Amino-1-phenylethanol; L-β-Phenyl-β-hydroxyethylamine
EINECS	221-679-8

Quality Control

Our L-Phenylglycinol is produced under a strict quality management system to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiles. Certificates of Analysis (COA) detailing specifications such as assay, optical rotation, and residual solvents are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]D20	-40° to -44° (c=1 in MeOH)
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.