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4-Fluoro-2-Methoxybenzoic Acid CAS NO 395-82-4


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CAS No.:395-82-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluoro-2-Methoxybenzoic Acid is a versatile fluorinated aromatic building block with a methoxy substituent, offering unique electronic and steric properties for advanced synthesis. This compound is crucial for medicinal chemistry research and the development of fine chemicals, where its structure serves as a key intermediate. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in constructing complex molecules for oncology and CNS disorders.
  • Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
  • Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
  • Polymer Modification: Employed to introduce fluorine and benzoic acid functionalities into polymers, improving their chemical resistance and surface properties.
  • Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for various fluorinated fine chemicals.
  • Chemical Research & Development: Essential for academic and industrial labs exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name 4-Fluoro-2-Methoxybenzoic Acid
CAS No. 395-82-4
Molecular Formula C8H7FO3
Molecular Weight 170.14 g/mol
Synonyms 2-Methoxy-4-fluorobenzoic Acid; 4-Fluoro-2-methoxybenzoic acid; 4-Fluoro-o-anisic Acid; 2-Methoxy-4-fluorobenzoic Acid; Benzoic acid, 4-fluoro-2-methoxy-; 4-Fluoro-2-methoxy-benzoic acid; FMEA
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Quality Control

Our 4-Fluoro-2-Methoxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point 158°C - 162°C
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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