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4-Fluoro-2-Methoxybenzoic Acid CAS NO 395-82-4
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CAS No.:395-82-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Fluoro-2-Methoxybenzoic Acid is a versatile fluorinated aromatic building block with a methoxy substituent, offering unique electronic and steric properties for advanced synthesis. This compound is crucial for medicinal chemistry research and the development of fine chemicals, where its structure serves as a key intermediate. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers for creating novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in constructing complex molecules for oncology and CNS disorders.
- Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
- Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
- Polymer Modification: Employed to introduce fluorine and benzoic acid functionalities into polymers, improving their chemical resistance and surface properties.
- Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for various fluorinated fine chemicals.
- Chemical Research & Development: Essential for academic and industrial labs exploring new fluorination methodologies and structure-activity relationships.
Basic Information
| Product Name | 4-Fluoro-2-Methoxybenzoic Acid |
| CAS No. | 395-82-4 |
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Synonyms | 2-Methoxy-4-fluorobenzoic Acid; 4-Fluoro-2-methoxybenzoic acid; 4-Fluoro-o-anisic Acid; 2-Methoxy-4-fluorobenzoic Acid; Benzoic acid, 4-fluoro-2-methoxy-; 4-Fluoro-2-methoxy-benzoic acid; FMEA |
| EINECS | Contact for details |
Quality Control
Our 4-Fluoro-2-Methoxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 158°C - 162°C |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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