Description

2-Fluoro-6-Nitrobenzoic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a carboxylic acid functional group, makes it a critical precursor for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and other advanced materials with specific electronic properties.
• Organic Synthesis Building Block: Utilized in various name reactions for introducing fluorine and nitro-substituted benzoic acid motifs into more complex structures.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of specialized dyes and pigments.

Basic Information

Product Name	2-Fluoro-6-Nitrobenzoic Acid
CAS No.	385-02-4
Molecular Formula	C7H4FNO4
Molecular Weight	185.11 g/mol
Synonyms	2-Fluoro-6-nitrobenzoic acid; 6-Nitro-2-fluorobenzoic acid; Benzoic acid, 2-fluoro-6-nitro-; 2-Fluoro-6-nitro-benzoic acid; 385-02-4; 2-Fluoro-6-nitrobenzoicacid; NSC 403119; 2-Fluoro-6-nitrobenzoic acid (9CI)
EINECS	206-850-3

Quality Control

Our 2-Fluoro-6-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.