Description

5-Fluoro-2-Nitrobenzoic Acid Ethyl Ester is a versatile fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluorine substituent, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and antibacterial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex fluorinated dyes and pigments with unique color properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, reductions, and nucleophilic substitutions to introduce functionalized benzoic acid derivatives.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Fluoro-2-Nitrobenzoic Acid Ethyl Ester
CAS No.	364-51-2
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Ethyl 5-Fluoro-2-nitrobenzoate; 2-Nitro-5-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 5-fluoro-2-nitro-, ethyl ester; Ethyl 5-fluoro-2-nitrobenzoate; 364-51-2; 5-Fluoro-2-nitro-benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Nitrobenzoic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.