Description

Galanthamine is a naturally occurring tertiary alkaloid, widely recognized for its potent and selective acetylcholinesterase inhibitory activity. This specific pharmacological profile makes it a critical active pharmaceutical ingredient (API) for the development of neurological therapeutics. It is primarily sought after by pharmaceutical manufacturers and research institutions focused on cognitive health and neurodegenerative conditions. Our supply of Galanthamine CAS NO 357-70-0 ensures high purity and consistent quality to meet stringent global regulatory standards.

Application

• Pharmaceutical API: Core ingredient in the formulation of medications for Alzheimer's disease and other forms of dementia.
• Neurological Research: A key reference standard and investigational compound in studies of cholinergic systems and neuroprotection.
• Biosynthesis Studies: Used in research exploring the alkaloid biosynthesis pathways within plants of the Amaryllidaceae family.
• Chemical Intermediate: Serves as a starting material or precursor for the semi-synthesis of novel derivatives with potential enhanced pharmacological properties.
• Reference Standard: Essential for quality control laboratories to perform assay validation, impurity profiling, and method development in pharmaceutical analysis.

Basic Information

Product Name	Galanthamine
CAS No.	357-70-0
Molecular Formula	C17H21NO3
Molecular Weight	287.35 g/mol
Synonyms	Galanthamine; Galantamine; Lycoremine; Jilkon; Nivalin; Reminyl; (-)-Galanthamine; (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
EINECS	206-614-0

Quality Control

Our Galanthamine is manufactured and tested under a strict quality management system. We ensure compliance with relevant pharmacopeial standards (such as USP/EP monographs where applicable) for identity, purity, and potency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing all critical quality attributes, including assay, related substances, residual solvents, and heavy metals. Our commitment to traceability and documentation supports your regulatory submissions and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	-118° to -122° (c=1 in ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.