Description

4-Fluoro-2-Hydroxybenzoic Acid is a versatile fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a phenolic hydroxyl group ortho to a fluorine atom, makes it a valuable intermediate for creating molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic displays and organic light-emitting diodes, improving performance characteristics.
• Complex Ligand & Catalyst Design: Serves as a starting material for synthesizing specialized chelating agents and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Incorporated into polymer chains to impart specific properties such as altered solubility, thermal stability, or chemical resistance.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	4-Fluoro-2-Hydroxybenzoic Acid
CAS No.	345-29-9
Molecular Formula	C7H5FO3
Molecular Weight	156.11 g/mol
Synonyms	2-Hydroxy-4-fluorobenzoic Acid; 4-Fluorosalicyllic Acid; 4-Fluoro-2-hydroxybenzenecarboxylic acid; 4-Fluorosalicylic Acid; NSC 403697; 4-Fluoro-2-hydroxy-benzoic acid; 4-Fluoro-2-hydroxybenzoic acid; 4-Fluoro-2-hydroxybenzoic acid (4-Fluorosalicylic acid)
EINECS	206-465-8

Quality Control

Our 4-Fluoro-2-Hydroxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.