Description

Methyl 2-(Trifluoromethyl)Benzoate is a versatile fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, which is highly sought after for modifying the physical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring the lipophilicity and metabolic stability conferred by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the CF3 moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes due to its influence on electronic properties and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface energy, chemical resistance, and optical characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a protecting group in complex multi-step synthetic routes.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D labs for exploring new fluorination methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	Methyl 2-(Trifluoromethyl)Benzoate
CAS No.	344-96-7
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	2-(Trifluoromethyl)benzoic acid methyl ester; Methyl o-trifluoromethylbenzoate; Benzoic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-(trifluoromethyl)benzoate; α,α,α-Trifluoro-o-toluic acid methyl ester; o-Trifluoromethylbenzoic acid methyl ester; Methyl α,α,α-trifluoro-o-toluate
EINECS	206-469-5

Quality Control

Our Methyl 2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is 2-25°C. The container must be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.460 - 1.470
Density (20°C)	1.28 - 1.32 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.