Description

Heptafluorobutyric Anhydride is a highly reactive perfluorinated acid anhydride, serving as a critical reagent for introducing the heptafluorobutyryl group. Its primary value lies in its powerful derivatization capability, which is essential for enhancing the detection and analysis of complex molecules in sensitive analytical techniques. This compound is particularly vital for analytical chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise and reliable derivatizing agents for gas chromatography and mass spectrometry.

Application

• Derivatization Agent for GC/MS Analysis: Used to derivative amines, alcohols, and phenols to improve their volatility, thermal stability, and detection sensitivity in gas chromatography-mass spectrometry.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and fluorinated drug candidates.
• Agrochemical Synthesis: Employed in the production of advanced fluorinated pesticides and herbicides, where the perfluorinated chain can influence bioavailability and environmental persistence.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty fluoropolymers, imparting unique properties like chemical resistance and low surface energy.
• Proteomics & Metabolomics Research: Utilized in sample preparation for the analysis of peptides, metabolites, and other biomolecules to enhance mass spectrometric identification.
• Liquid Scintillation Counting: Can be used in the preparation of fluorinated compounds for specific detection applications in radiochemistry.

Basic Information

Product Name	Heptafluorobutyric Anhydride
CAS No.	336-59-4
Molecular Formula	C8F14O3
Molecular Weight	410.06 g/mol
Synonyms	Perfluorobutyric Anhydride; Heptafluorobutyric Acid Anhydride; 2,2,3,3,4,4,4-Heptafluorobutyric Anhydride; HFBA; Perfluorobutanoic Anhydride; NSC 9235; UN 3265
EINECS	206-396-8

Quality Control

Our Heptafluorobutyric Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for analytical and synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.300 - 1.310
Density (20°C)	1.65 - 1.75 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.