Description

4-(Trifluoromethoxy)Benzoic Acid is a versatile fluorinated aromatic building block characterized by its benzoic acid core and trifluoromethoxy substituent. This compound is valued for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in synthesizing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the trifluoromethoxy pharmacophore.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine-containing group improves biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Modification: Incorporated as a monomer or additive to enhance the chemical resistance and stability of specialty polymers.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide couplings to construct complex organic molecules in R&D settings.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new reactions and material properties facilitated by the trifluoromethoxy group.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzoic Acid
CAS No.	330-12-1
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	p-(Trifluoromethoxy)benzoic acid; 4-(Trifluoromethoxy)benzoic acid; Benzoic acid, 4-(trifluoromethoxy)-; α,α,α-Trifluoro-p-anisic acid; 4-Carboxytrifluoromethoxybenzene; Trifluoromethoxybenzoic acid; TFMOBA; F3CO-Ph-COOH
EINECS	206-352-7

Quality Control

Our 4-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	156 - 160 °C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.