Description

4-(Trifluoromethoxy)Benzoyl Fluoride is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is critical for introducing the 4-(trifluoromethoxy)benzoyl moiety into target molecules, a key step in developing compounds with enhanced biological activity and stability. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group imparts improved lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer & Material Science: Employed in the development of specialty polymers, coatings, and advanced materials requiring specific fluorine-containing aromatic units.
• Organic Synthesis Reagent: Acts as a versatile acylating agent in research laboratories for the preparation of amides, esters, and ketones under mild conditions.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzoyl Fluoride
CAS No.	330-11-0
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	p-(Trifluoromethoxy)benzoyl fluoride; 4-(Trifluoromethoxy)benzoic acid fluoride; α,α,α-Trifluoro-p-anisoyl fluoride; 4-(Trifluoromethoxy)benzoyl fluoride; 330-11-0; Benzoyl fluoride, 4-(trifluoromethoxy)-; EINECS 206-350-8
EINECS	206-350-8

Quality Control

Our 4-(Trifluoromethoxy)Benzoyl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.