Description

Methyl 4-Fluoro-3-Nitrobenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides where the fluorine and nitro groups impart specific activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Synthesis Building Block: Utilized in Suzuki-Miyaura and other cross-coupling reactions to introduce the 4-fluoro-3-nitrobenzoate moiety into more complex structures.
• Dye and Pigment Research: Acts as an intermediate in the development of specialized fluorinated dyes and functional pigments.
• Material Science Research: Employed in the creation of novel polymers and advanced organic materials with tailored electronic properties.

Basic Information

Product Name	Methyl 4-Fluoro-3-Nitrobenzoate
CAS No.	329-59-9
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	4-Fluoro-3-nitrobenzoic acid methyl ester; Methyl 4-fluoro-3-nitrobenzoate; Benzoic acid, 4-fluoro-3-nitro-, methyl ester; 3-Nitro-4-fluorobenzoic acid methyl ester; Methyl 3-nitro-4-fluorobenzoate; 4-Fluoro-3-nitro-methylbenzoate; Methyl p-fluoro-m-nitrobenzoate; CAS 329-59-9
EINECS	206-343-6

Quality Control

Our production of Methyl 4-Fluoro-3-Nitrobenzoate adheres to stringent quality management protocols. Each batch is analytically verified to ensure high chemical purity and consistency, supported by a comprehensive Certificate of Analysis (COA). We maintain traceability and compliance with relevant global chemical regulations, including REACH. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.