Description

4-Fluoro-2-Methylbenzoic Acid is a versatile fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and a carboxylic acid functional group onto a methyl-substituted benzene ring, enabling precise modulation of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & Material Science: Serves as a precursor in the synthesis of fluorinated liquid crystals and advanced organic materials for electronic displays.
• Organic Synthesis Building Block: Employed in various coupling reactions (e.g., Suzuki, Heck) and as a precursor for corresponding acid chlorides, esters, and amides.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	4-Fluoro-2-Methylbenzoic Acid
CAS No.	321-21-1
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	2-Methyl-4-fluorobenzoic acid; 4-Fluoro-o-toluic acid; 4-Fluoro-2-methylbenzoic acid; Benzoic acid, 4-fluoro-2-methyl-; 4-Fluoro-2-toluic acid; 2-Methyl-4-fluorobenzoic acid; 4-Fluoro-2-methylbenzoic acid; 321-21-1
EINECS	206-281-5

Quality Control

Our 4-Fluoro-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.