Description

4-Fluorophthalic Acid is a high-purity fluorinated aromatic dicarboxylic acid building block, essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs). Its unique structure, featuring both a carboxylic acid and a fluorine substituent, enables precise molecular design and functionalization in demanding chemical processes. This compound is critical for research and production in the pharmaceutical, agrochemical, and specialty polymer industries, where it serves as a key intermediate for creating compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a key monomer for synthesizing fluorinated polyimides and other polymers used in high-performance displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine and carboxylic acid functionality into polymers, improving their thermal stability, chemical resistance, and surface properties.
• Metal-Organic Framework (MOF) Precursor: Acts as an organic linker in the construction of novel MOFs for gas storage, separation, and catalysis applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	4-Fluorophthalic Acid
CAS No.	320-97-8
Molecular Formula	C8H5FO4
Molecular Weight	184.12 g/mol
Synonyms	4-Fluorobenzene-1,2-dicarboxylic Acid; 1,2-Benzenedicarboxylic Acid, 4-Fluoro-; 4-Fluorophthalic Acid; 4-Fluoroisophthalic Acid (common misnomer); 4-Fluorobenzene-o-dicarboxylic Acid; o-Carboxy-4-fluorobenzoic Acid; 4-Fluoro-1,2-benzenedicarboxylic Acid; FPA
EINECS	206-280-5

Quality Control

Our 4-Fluorophthalic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the highest standards. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture from the air, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	210°C - 215°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.