Description

4-Nitro-2-(Trifluoromethyl)Benzoic Acid is a versatile aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a nitro and a trifluoromethyl group, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules and nonlinear optical (NLO) chromophores.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of fluorine substitution on reaction pathways and molecular properties.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-Nitro-2-(Trifluoromethyl)Benzoic Acid
CAS No.	320-37-6
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	2-(Trifluoromethyl)-4-nitrobenzoic acid; 4-Nitro-α,α,α-trifluoro-o-toluic acid; Benzoic acid, 4-nitro-2-(trifluoromethyl)-; 4-Nitro-2-trifluoromethylbenzoic acid; 2-Trifluoromethyl-4-nitrobenzoic acid; 4-Nitro-α,α,α-trifluoro-2-methylbenzoic acid; NSC 404087
EINECS	206-276-7

Quality Control

Our 4-Nitro-2-(Trifluoromethyl)Benzoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.