Description

4-Bromo-2-(Trifluoromethyl) Benzoic Acid is a high-purity, multifunctional aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Active Ingredient Precursor: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging the unique properties of the trifluoromethyl group.
• Ligand Synthesis for Catalysis: Serves as a starting material for constructing sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where specific halogenated aromatic units are required.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, photoaffinity labels, and other molecular probes for biological research.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl) Benzoic Acid
CAS No.	320-31-0
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	2-(Trifluoromethyl)-4-bromobenzoic acid; 4-Bromo-α,α,α-trifluoro-o-toluic acid; Benzoic acid, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-2-trifluoromethylbenzoic acid; 4-Bromo-α,α,α-trifluoro-2-methylbenzoic acid; 2-Trifluoromethyl-4-bromobenzoic acid; 4-Bromo-2-(trifluoromethyl)benzenecarboxylic acid
EINECS	206-274-9

Quality Control

Our 4-Bromo-2-(Trifluoromethyl) Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.