Description

2-Amino-5-Fluorobenzoic Acid Methyl Ester is a key fluorinated aromatic building block, essential for synthesizing complex molecules. Its value lies in the strategic combination of an amino group and a fluorine atom on the benzoic acid ester scaffold, enabling precise structural modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for anticancer, antiviral, and CNS-targeting drugs.
• Agrochemical Synthesis: Used to build advanced intermediates for novel herbicides, fungicides, and pesticides, where the fluorine atom enhances bioactivity and environmental stability.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocycles and fine chemicals via reactions at the amino and ester functional groups.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components.
• Dye and Pigment Intermediate: Acts as a key substrate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Amino-5-Fluorobenzoic Acid Methyl Ester
CAS No.	319-24-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Methyl 2-Amino-5-fluorobenzoate; 5-Fluoroanthranilic Acid Methyl Ester; 2-Amino-5-fluorobenzoic Acid Methyl Ester; Methyl 5-Fluoroanthranilate; 5-Fluoro-2-aminobenzoic Acid Methyl Ester; Benzoic acid, 2-amino-5-fluoro-, methyl ester; Methyl (2-amino-5-fluorophenyl)carboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluorobenzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.