Description

1-α-H,5-α-H-Tropan-3-α-Ol, (+)-Tropate (Ester), Sulfate (2 :1) (Salt) is a high-purity, pharmacologically significant tropane alkaloid salt. This compound is essential for research and development in the pharmaceutical sector, particularly for its role as a key intermediate and reference standard. It is primarily sought after by manufacturers and research institutions engaged in neuropharmacology, analytical chemistry, and the development of anticholinergic agents. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency and reliability for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex therapeutic agents, particularly those targeting the nervous system.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, GC-MS, and other analytical techniques.
• Biochemical Research: Employed in receptor binding studies and pharmacological research to investigate anticholinergic mechanisms and pathways.
• Active Pharmaceutical Ingredient (API) Development: Acts as a precursor in the development and manufacturing of specific pharmaceutical formulations.
• Academic & Industrial R&D: Utilized in universities and corporate labs for exploratory chemistry and the development of new chemical entities.

Basic Information

Product Name	1-α-H,5-α-H-Tropan-3-α-Ol, (+)-Tropate (Ester), Sulfate (2 :1) (Salt)
CAS No.	300-40-3
Molecular Formula	C17H21NO4 · ½H2SO4
Molecular Weight	305.36 g/mol (free base) / Contact for details (salt)
Synonyms	Atropine Sulfate; Atropine Sulphate; dl-Hyoscyamine Sulfate; Tropine Tropate Sulfate; (±)-Hyoscyamine Sulfate; 3α-Tropanyl (±)-tropate Sulfate; Endotropin; Atropinol
EINECS	206-104-4

Quality Control

Our 1-α-H,5-α-H-Tropan-3-α-Ol, (+)-Tropate (Ester), Sulfate (2 :1) (Salt) is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and identification. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (Titration)	Positive test for sulfate
Assay (HPLC)	≥ 98.5% (on anhydrous basis)
Loss on Drying	≤ 1.0 %
Specific Rotation	-0.3° to +0.3° (c = 5 in H2O)
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.