Description

(R)-2,2,2-Trifluoro-1-(3-Methoxyphenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block, essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals. Its value lies in the trifluoromethyl and methoxy substituents, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique fluorinated properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(R)-2,2,2-Trifluoro-1-(3-Methoxyphenyl)Ethanamine Hydrochloride
CAS No.	2829292-55-7
Molecular Formula	C9H11ClF3NO
Molecular Weight	241.64 g/mol
Synonyms	(R)-1-(3-Methoxyphenyl)-2,2,2-trifluoroethanamine hydrochloride; (R)-α-(Trifluoromethyl)-3-methoxybenzylamine hydrochloride; (R)-3-Methoxy-α-(trifluoromethyl)benzylamine hydrochloride; (R)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethan-1-amine hydrochloride; (R)-TFMPEA HCl; (R)-1-(3-Methoxyphenyl)-2,2,2-trifluoroethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2,2,2-Trifluoro-1-(3-Methoxyphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.