Description

2-Propanesulfinamide, n-[(S)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Phenylmethyl]-N,2-Dimethyl-, [S(R)]- is a sophisticated chiral ligand and organocatalyst, specifically designed for asymmetric synthesis. This compound matters for its ability to impart high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the production of single-enantiomer intermediates. Pharmaceutical R&D laboratories and fine chemical manufacturers specializing in active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials are the primary users who need this high-value reagent.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation and cross-coupling reactions.
• As an organocatalyst for enantioselective additions to imines and carbonyl compounds.
• Critical for the synthesis of single-enantiomer pharmaceutical intermediates, including chiral amines and amino acid derivatives.
• Used in the research and development of novel agrochemicals requiring specific stereochemistry for biological activity.
• Facilitates the preparation of advanced materials with chiral properties for optoelectronic applications.
• Employed in methodology development within academic and industrial organic chemistry laboratories.

Basic Information

Product Name	2-Propanesulfinamide, n-[(S)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Phenylmethyl]-N,2-Dimethyl-, [S(R)]-
CAS No.	2757083-10-4
Molecular Formula	C39H38NO2PS
Molecular Weight	615.77 g/mol
Synonyms	(S)-N-[(S)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-N,2-dimethylpropane-2-sulfinamide; (SR)-N-[(S)-[4-(Diphenylphosphino)-9,9-dimethylxanthen-9-yl]phenylmethyl]-N,2-dimethylpropane-2-sulfinamide; XantPhos-Sulfinamide Ligand; Chiral XantPhos Sulfinamide Derivative; (SR,S)-Sulfinamide-XantPhos Hybrid Ligand; Asymmetric Sulfinamide Catalyst; CAS 2757083-10-4
EINECS	Contact for details

Quality Control

This high-purity chiral chemical is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. Keep the container in a cool, dry, and well-ventilated place, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.