Description

2-Propanesulfinamide, n-[(R)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Phenylmethyl]-2-Methyl-, [S(R)]- is a sophisticated chiral ligand and organocatalyst, crucial for enabling highly selective and efficient asymmetric synthesis. Its value lies in its ability to induce precise stereochemical control in complex chemical transformations, a critical requirement for producing high-value intermediates in regulated industries. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity catalysts to develop novel active ingredients and functional molecules.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and allylic substitution.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions in fine chemical synthesis.
• Critical component in the research and development of new active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Use in the synthesis of agrochemical intermediates where biological activity is stereospecific.
• Production of specialty chemicals and advanced materials with chiral properties.
• Tool compound for methodology development in academic and industrial organic chemistry laboratories.

Basic Information

Product Name	2-Propanesulfinamide, n-[(R)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Phenylmethyl]-2-Methyl-, [S(R)]-
CAS No.	2757083-08-0
Molecular Formula	C38H36NO2PS
Molecular Weight	601.74 g/mol
Synonyms	(SR)-N-[(R)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-2-methylpropane-2-sulfinamide; Xantphos-Derived Chiral Sulfinamide Ligand; Chiral Xantphos-Sulfinamide Hybrid Ligand; (R)-DTBM-SEGPHOS-Type Sulfinamide Analog; Asymmetric Synthesis Ligand 2757083-08-0; N-[(R)-[5-(Diphenylphosphino)-9,9-Dimethylxanthen-4-yl](phenyl)methyl]-2-methylpropane-2-sulfinamide; [S(R)]-2-Methyl-N-[(R)-[5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]propane-2-sulfinamide
EINECS	Contact for details

Quality Control

Our production of this advanced chiral compound adheres to strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and chiral purity analysis. A Certificate of Analysis (COA) detailing identity, purity (typically >97%), and chiral excess is provided with each shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool environment. Due to its hygroscopic and easily oxidized nature, the container should only be opened in a controlled, moisture-free atmosphere and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.