Description

Ensitrelvir is a potent and selective oral antiviral agent, specifically a 3C-like protease inhibitor. This compound is of significant commercial and therapeutic interest for its targeted mechanism of action against viral replication. It is primarily required by pharmaceutical R&D departments, contract manufacturing organizations (CMOs), and academic research institutions engaged in antiviral drug development and production.

Application

• Active Pharmaceutical Ingredient (API): Serves as the core active component in the formulation of finished antiviral medications.
• Pharmaceutical Research & Development: Used as a reference standard and key intermediate in the discovery and optimization of novel antiviral therapies.
• Preclinical and Clinical Studies: Essential for conducting pharmacological, toxicological, and clinical trials to establish safety and efficacy profiles.
• Antiviral Mechanism Studies: Employed in biochemical and virological assays to study protease inhibition and viral resistance mechanisms.
• Contract Manufacturing: Supplied to CMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for commercial supply.

Basic Information

Product Name	Ensitrelvir
CAS No.	2647530-73-0
Molecular Formula	C26H19F2N3O5S
Molecular Weight	499.51 g/mol
Synonyms	Ensitrelvir; S-217622; Xocova; (1R,2S,5S)-N-[(1S)-1-Cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl]-6,6-difluoro-3-[(2-fluorophenyl)sulfonyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide; 3CL protease inhibitor S-217622; SARS-CoV-2 3CLpro inhibitor S-217622
EINECS	Contact for details

Quality Control

Our Ensitrelvir is manufactured and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.