Description

Retinol 19,19,19,20,20,20-D6 is a high-purity, deuterium-labeled isotopologue of Vitamin A (Retinol), specifically designed for use as an internal standard in quantitative mass spectrometry. This compound is critical for ensuring analytical accuracy and reproducibility in research and quality control laboratories. It is primarily utilized by scientists and manufacturers in the pharmaceutical, nutraceutical, and life science sectors for precise metabolic studies, pharmacokinetic analysis, and the quantification of retinol and its derivatives in complex matrices.

Application

• Internal Standard for LC-MS/MS: Essential for the accurate quantification of endogenous retinol and related compounds in biological samples (e.g., serum, plasma, tissues).
• Metabolic Pathway Tracing: Used in stable isotope labeling studies to investigate Vitamin A absorption, distribution, metabolism, and excretion (ADME).
• Pharmaceutical R&D: Supports the development and bioanalysis of retinoid-based drugs, ensuring precise measurement of drug and metabolite levels.
• Clinical Research: Enables reliable measurement of Vitamin A status in nutritional and epidemiological studies.
• Nutraceutical & Food Analysis: Facilitates the accurate assay of Vitamin A content and stability in fortified foods and dietary supplements.
• Reference Material: Serves as a certified reference material (CRM) for method validation and laboratory proficiency testing.

Basic Information

Product Name	Retinol 19,19,19,20,20,20-D6
CAS No.	2483831-77-0
Molecular Formula	C₂₀H₂₄D₆O
Molecular Weight	292.48 g/mol
Synonyms	Vitamin A-d6; all-trans-Retinol-d6; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol-d6; 19,19,19,20,20,20-Hexadeutero-retinol; Deuterated Retinol; Retinol Internal Standard; Isotopically Labeled Vitamin A
EINECS	Contact for details

Quality Control

Every batch of Retinol 19,19,19,20,20,20-D6 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity as verified by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (argon or nitrogen). This product is light-sensitive and easily oxidized; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or oil
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98% (Area%)
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.