Description

4-(Cyclohexylaminomethyl)-3-Fluorophenylboronic Acid Pinacol Ester is a sophisticated organoboron building block designed for advanced synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. Pharmaceutical researchers and agrochemical developers need it for creating novel active ingredients, particularly in medicinal chemistry programs targeting challenging biological pathways.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, especially those requiring fluorinated and functionalized aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is crucial.
• Ligand and Catalyst Development: Useful for constructing complex ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biological target identification and validation.

Basic Information

Product Name	4-(Cyclohexylaminomethyl)-3-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2377610-79-0
Molecular Formula	C19H29BFNO2
Molecular Weight	333.26 g/mol
Synonyms	[4-(Cyclohexylaminomethyl)-3-fluorophenyl]boronic acid pinacol ester; 3-Fluoro-4-[(cyclohexylamino)methyl]benzeneboronic acid pinacol ester; B-[4-[(Cyclohexylamino)methyl]-3-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-[(cyclohexylamino)methyl]-3-fluorophenyl]-1,3,2-dioxaborolane; Pinacol [4-(cyclohexylaminomethyl)-3-fluorophenyl]boronate; Boronic ester derivative of 3-fluoro-4-(cyclohexylaminomethyl)benzene; CAS 2377610-79-0
EINECS	Contact for details

Quality Control

Our 4-(Cyclohexylaminomethyl)-3-Fluorophenylboronic Acid Pinacol Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.