Description

4-(Piperazino)Methylphenylboronic Acid Pinacol Ester Hcl is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is valued for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and complex organic molecules, particularly in medicinal chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in Suzuki-Miyaura cross-coupling reactions and other boron-mediated transformations.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile boronic ester partner for constructing biaryl and heterobiaryl structures central to many modern pharmaceuticals.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery pipelines.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced crop protection agents and herbicides.
• Material Science Precursor: Used in the research and development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for biochemical and diagnostic applications.

Basic Information

Product Name	4-(Piperazino)Methylphenylboronic Acid Pinacol Ester Hcl
CAS No.	2377610-73-4
Molecular Formula	C18H30BClN2O2
Molecular Weight	352.71 g/mol
Synonyms	4-(Piperazin-1-ylmethyl)phenylboronic acid pinacol ester hydrochloride; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperazine hydrochloride; 4-(Piperazin-1-ylmethyl)benzeneboronic acid pinacol ester HCl; 4-(Piperazinomethyl)phenylboronic acid pinacol ester hydrochloride; (4-((Piperazin-1-yl)methyl)phenyl)boronic acid pinacol ester hydrochloride; Boronic acid, B-[4-[(1-piperazinyl)methyl]phenyl]-, 1,1-dimethylethyl ester, hydrochloride; CAS 2377610-73-4
EINECS	Contact for details

Quality Control

Our 4-(Piperazino)Methylphenylboronic Acid Pinacol Ester Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your GMP and research documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.