Description

(5-Chloro-2-Fluoro-3-Methoxyphenyl)Boronic Acid is a high-purity, multi-substituted arylboronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, which are fundamental to pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED emitters and charge-transport molecules.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-Chloro-2-Fluoro-3-Methoxyphenyl)Boronic Acid
CAS No.	2377610-22-3
Molecular Formula	C7H7BClFO3
Molecular Weight	203.39 g/mol
Synonyms	(5-Chloro-2-fluoro-3-methoxyphenyl)boronic acid; Boronic acid, B-(5-chloro-2-fluoro-3-methoxyphenyl)-; 5-Chloro-2-fluoro-3-methoxybenzeneboronic acid; 3-Methoxy-5-chloro-2-fluorophenylboronic acid; 2-Fluoro-5-chloro-3-methoxyphenylboronic acid; CAS 2377610-22-3
EINECS	Contact for details

Quality Control

Our (5-Chloro-2-Fluoro-3-Methoxyphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.