Description

5-Chloro-2,3-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for Suzuki-Miyaura and other palladium-catalyzed couplings.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates containing complex biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated phenyl motifs.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Product Name	5-Chloro-2,3-Difluorophenylboronic Acid
CAS No.	2377610-07-4
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(5-Chloro-2,3-difluorophenyl)boronic Acid; 5-Chloro-2,3-difluorobenzeneboronic Acid; Boronic acid, B-(5-chloro-2,3-difluorophenyl)-; 2377610-07-4; 5-Chloro-2,3-difluoro phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2,3-Difluorophenylboronic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.