Description

5-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in next-generation herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized boronic ester ligands and organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED and OFET components, where the bromo and fluoro substituents fine-tune electronic properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and bioconjugation reagents due to its reactive boronic acid group.
• Custom Synthesis & Contract Manufacturing: A vital raw material for CROs and CDMOs offering bespoke chemical synthesis services for client projects.

Basic Information

Product Name	5-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid
CAS No.	2377610-06-3
Molecular Formula	C7H7BBrFO3
Molecular Weight	247.85 g/mol
Synonyms	(5-Bromo-2-fluoro-3-methoxyphenyl)boronic acid; 5-Bromo-2-fluoro-3-methoxybenzeneboronic acid; 2-Fluoro-5-bromo-3-methoxybenzeneboronic acid; Boronic acid, B-(5-bromo-2-fluoro-3-methoxyphenyl)-; CAS 2377610-06-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.