Description

5-Carboxy-2-Fluoro-3-Methoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced chemical synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or functionalizing agent for creating advanced polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and asymmetric synthesis.
• Bioconjugation and Probe Synthesis: Utilized for attaching fluorophores or other reporter groups to biomolecules for diagnostic applications.
• Academic and Contract Research: Essential for exploratory chemistry in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	5-Carboxy-2-Fluoro-3-Methoxyphenylboronic Acid
CAS No.	2377609-80-6
Molecular Formula	C9H8BFO5
Molecular Weight	225.97 g/mol
Synonyms	3-Methoxy-2-fluoro-5-carboxyphenylboronic acid; (5-Carboxy-2-fluoro-3-methoxyphenyl)boronic acid; 2-Fluoro-3-methoxy-5-boronobenzoic acid; 5-Borono-2-fluoro-3-methoxybenzoic acid; CAS 2377609-80-6; B-(5-Carboxy-2-fluoro-3-methoxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 5-Carboxy-2-Fluoro-3-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 15-25°C. Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.