Description

(5-(Benzyloxy)-6-Fluoropyridin-3-Yl)Boronic Acid is a high-value, multifunctional boronic acid derivative used as a key synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by incorporating the fluorinated pyridine scaffold into lead compounds.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, including polymers for OLEDs and sensors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Ligand Synthesis: Acts as a precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-(Benzyloxy)-6-Fluoropyridin-3-Yl)Boronic Acid
CAS No.	2377609-45-3
Molecular Formula	C₁₂H₁₁BFNO₃
Molecular Weight	247.03 g/mol
Synonyms	5-(Benzyloxy)-6-fluoro-3-pyridineboronic acid; 6-Fluoro-5-(phenylmethoxy)-3-pyridineboronic acid; (5-Benzyloxy-6-fluoropyridin-3-yl)boronic acid; 3-Borono-5-(benzyloxy)-6-fluoropyridine; B-[5-(Benzyloxy)-6-fluoro-3-pyridinyl]boronic acid; 2377609-45-3; (5-(Benzyloxy)-6-fluoropyridin-3-yl)borinic acid
EINECS	Contact for details

Quality Control

Our (5-(Benzyloxy)-6-Fluoropyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We adhere to relevant industry standards and can support development under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.