Description

(3-Bromo-2,4-Difluorophenyl)Boronic Acid is a high-purity, multifunctional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the introduction of the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs or OFETs, where precise control over molecular structure is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors, leveraging boronic acid's affinity for diols.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical producers for custom synthesis projects requiring high-fidelity coupling reactions.

Basic Information

Product Name	(3-Bromo-2,4-Difluorophenyl)Boronic Acid
CAS No.	2377609-38-4
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(3-Bromo-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-3-bromophenylboronic acid; 3-Bromo-2,4-difluorobenzeneboronic acid; Boronic acid, B-(3-bromo-2,4-difluorophenyl)-; (3-Br-2,4-F2-Ph)B(OH)2; CAS 2377609-38-4
EINECS	Contact for details

Quality Control

Our (3-Bromo-2,4-Difluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.