Description

4-Cyano-2,3-Difluorophenylboronic Acid is a high-value boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials used in displays and lighting.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functionalized materials with tailored properties.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and enzyme inhibitors for biochemical research.
• Cross-Coupling Reactions: Primarily used in Suzuki-Miyaura cross-coupling to introduce the 4-cyano-2,3-difluorophenyl moiety into complex molecules.

Basic Information

Product Name	4-Cyano-2,3-Difluorophenylboronic Acid
CAS No.	2377608-51-8
Molecular Formula	C7H4BF2NO2
Molecular Weight	182.93 g/mol
Synonyms	(4-Cyano-2,3-difluorophenyl)boronic acid; 2,3-Difluoro-4-cyanophenylboronic acid; B-(4-Cyano-2,3-difluorophenyl)boronic acid; 4-Cyano-2,3-difluorobenzeneboronic acid; 2377608-51-8; 4-CN-2,3-F2-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Cyano-2,3-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.