Description

3-Oxetanemethanol, α-Methyl-, (αr)- is a high-purity chiral oxetane derivative, a valuable building block in modern synthetic chemistry. Its significance lies in its unique oxetane ring, which is increasingly used in medicinal chemistry to improve the metabolic stability and physicochemical properties of drug candidates. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients. It is supplied with a Certificate of Analysis to ensure batch-to-batch consistency for critical R&D and scale-up applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, where the oxetane moiety can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel polymers and functional materials with tailored properties.
• Academic & Industrial R&D: A versatile building block for method development and exploring new chemical spaces in process chemistry.

Basic Information

Item	Detail
Product Name	3-Oxetanemethanol, α-Methyl-, (αr)-
CAS No.	2375165-27-6
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(R)-3-(Hydroxymethyl)-3-methyloxetane; (R)-3-Methyl-3-oxetanemethanol; α-Methyl-3-oxetanemethanol (R)-; (R)-3-Methyloxetane-3-methanol; Oxetane-3-methanol, 3-methyl-, (3R)-; (3R)-3-Methyloxetane-3-carbinol; Chiral Oxetane Alcohol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3-Oxetanemethanol, α-Methyl-, (αr)- is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, Chiral HPLC, and NMR to ensure identity, purity, and enantiomeric excess meet the highest standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality protocols are designed to support cGMP for pharmaceutical applications and ensure compliance with global regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.