Description

Molnupiravir CAS NO 2349386-89-4 is a potent antiviral prodrug, specifically a ribonucleoside analog, designed to inhibit the replication of RNA viruses. Its primary value lies in its mechanism of action, which introduces copying errors during viral RNA synthesis, making it a critical tool in antiviral research and therapeutic development. This compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on virology, infectious disease treatment, and the development of broad-spectrum antiviral agents.

Application

• Antiviral Pharmaceutical Research: Primary active pharmaceutical ingredient (API) in the development of oral antiviral medications.
• Virology Studies: Used as a reference standard and research tool to study viral replication mechanisms and resistance profiles.
• Preclinical and Clinical Development: Serves as the key material for formulation studies, pharmacokinetic/pharmacodynamic (PK/PD) modeling, and clinical trial material (CTM) manufacturing.
• Infectious Disease Therapeutics: Targeted for the treatment of RNA virus infections, including specific coronavirus strains.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) assays to discover and evaluate new antiviral compounds.
• Process Chemistry & Scale-Up: Serves as the target molecule for optimizing synthetic routes and manufacturing processes under GMP conditions.

Basic Information

Product Name	Molnupiravir
CAS No.	2349386-89-4
Molecular Formula	C13H19N3O7
Molecular Weight	329.31 g/mol
Synonyms	EIDD-2801; MK-4482; N4-Hydroxycytidine isopropyl ester; β-D-N4-Hydroxycytidine isopropyl ester; Isopropyl (2R,3S,4R,5R)-2-(4-hydroxyamino-2-oxopyrimidin-1-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-3-carboxylate; Molnupiravir (USAN); 1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-((hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxyamino-2(1H)-pyrimidinone isopropyl ester
EINECS	Contact for details

Quality Control

Our Molnupiravir is manufactured and tested to meet high-purity standards suitable for pharmaceutical research and development. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and control of specific impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results against established specifications. We support development under quality systems aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.