Description

2-(2,4,6-Trifluorophenyl)Cyclopropane-1-Carboxylic Acid is a high-value fluorinated cyclopropane derivative, a key structural motif in modern organic synthesis. This compound is prized for its role as a versatile and sophisticated building block in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a trifluoromethylphenyl-cyclopropyl moiety into complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides, where the fluorinated cyclopropane structure enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Used in the research and preparation of specialized ligands and organocatalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed as a monomer or additive in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-(2,4,6-Trifluorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	2228449-24-7
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	2-(2,4,6-Trifluorophenyl)cyclopropanecarboxylic acid; 2-(2,4,6-Trifluorophenyl)-1-cyclopropanecarboxylic Acid; 1-Cyclopropanecarboxylic acid, 2-(2,4,6-trifluorophenyl)-; (2-(2,4,6-Trifluorophenyl)cyclopropyl)carboxylic acid; α-(2,4,6-Trifluorophenyl)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(2,4,6-Trifluorophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its chemical nature, it should be handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.