Description

(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2'-Dimethyl-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole CAS NO 2214207-74-4 is a high-purity, chiral organophosphorus compound characterized by its unique binaphthol-derived oxaphosphole structure. This compound matters as a sophisticated ligand precursor or catalyst in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled synthesis of complex active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Potential application in the synthesis of chiral polymers or as a dopant for liquid crystal displays (LCDs).
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2'-Dimethyl-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	2214207-74-4
Molecular Formula	C28H38O2P2
Molecular Weight	468.53 g/mol
Synonyms	(R,R)-3,3'-Di-tert-butyl-2,2'-dimethyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; (R,R)-DTB-BOXAP; Chiral Binaphthol Oxaphosphole Derivative; P-Chiral Bisphosphonite Ligand Precursor; (2R,2'R,3R,3'R)-DTB-Me-BIBOP; (R,R)-3,3'-Di-t-butyl-2,2'-dimethyl-2,2',3,3'-tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole
EINECS	Contact for details

Quality Control

Our (2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2'-Dimethyl-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.