Description

(3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bi-1,3-Benzoxaphosphole CAS NO 2214207-73-3 is a high-purity, chiral organophosphorus compound characterized by its unique binaphthol-derived structure. This compound is valued for its role as a sophisticated ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, C-C bond formation, and oxidation.
• As a key building block or catalyst precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess.
• In the development of novel agrochemicals where specific stereochemistry is crucial for biological activity.
• For research and development of advanced materials, including chiral polymers and liquid crystals.
• As a standard or reference compound in analytical method development for chiral separation techniques (e.g., HPLC, SFC).
• In academic and industrial research exploring new methodologies in organocatalysis and supramolecular chemistry.

Basic Information

Product Name	(3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bi-1,3-Benzoxaphosphole
CAS No.	2214207-73-3
Molecular Formula	C28H34O2P2
Molecular Weight	464.51 g/mol
Synonyms	(R,R)-3,3'-Di-tert-butyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; (R,R)-3,3'-Di-t-butyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; (3R,3'R)-3,3'-Di-tert-butyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; (R,R)-DTB-BINAP(O); Chiral Binaphthol-Based Phosphole; 2,2',3,3'-Tetrahydro-4,4'-bi-1,3-benzoxaphosphole, 3,3'-bis(1,1-dimethylethyl)-, (3R,3'R)-
EINECS	Contact for details

Quality Control

Our (3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bi-1,3-Benzoxaphosphole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and chiral assay are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.